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ARTICULATE, TO THE POINT, EPIDEMIOLOGICAL AND HEALTH ECONOMIC ANALYSES.

Our clients are scientists and decision-makers fighting against infectious diseases. We equip them with the clarity and depth they need to carry out their mission.

We do epidemiological and health economic modeling

We specialize in infectious disease epidemiological transmission models and health economic analyses.

Epidemiological transmission models are numerical models describing how infectious diseases spread in populations.

Health economic models translate the epidemiological impact of interventions in terms of costs, benefits, and quality of life.

Spegegant leverages epidemiological and health economic modeling in two broad areas: market access, and epidemic prevention and control.

For market access

Market access services support product launch preparation starting from early development phases. We help to demonstrate the burden of diseases, raise awareness, and estimate the potential impact of a new product.

We contribute to competitive positioning and strategic fit assessment, bridging the gap between available clinical data and value demonstration, and simulating prospective scenarios.

We help our clients understand existing modeling approaches, whether published by competitors or recommended by authorities, and perceive their business implications.

We provide guidance to address questions from public health agencies or NITAGs, but also from internal stakeholders and teams.

Product development may span over years. At each stage, we fit in where we are needed and play nicely with all teams involved.

Capabilities

Model development "from scratch"

Model sanity check and optimization

Model adaptation

Technical deep dives / analysis of existing models

Value assessment of health products (e.g. cost-effectiveness)

Analysis of modeling guidelines

For epidemic prevention and control

We assist decision-makers in picking the right strategy to control epidemics, mitigate risk, and meet public health or operational objectives.

Health interventions are often irreversible, subject to uncertainty, and to operational constraints. Numerical modeling and simulations are necessary to explore large numbers of strategies that cannot be tested in the field, all while taking uncertainties into account.

Capabilities

Simulation and comparison of prevention or control strategies

Value assessment of interventions

"What-if" analyses

Decision-analytic modeling under uncertainty

Analysis of disease transmission mechanisms

Data acquisition strategy / clinical trial design

We are small and nimble

Spegegant takes a task force approach to work. Acting as our clients' co-pilots, we are able to start fast and deliver insights on the fly in a changing environment. We implement technical solutions that are proportionate to the problem at hand – no overkill, no one-fits-all tool.

Spegegant stands for specialia generalibus derogant, the specific derogates from the general. We offer targeted analyses to our clients, whether in market access or for epidemic prevention and control.

Spegegant does not operate as one-stop shop. We support our clients with on-demand advice and guidance in our core areas of expertise: infectious disease transmission modeling and health economics.

We can address related, technically close, topics (e.g. within-host modeling).

We are able to investigate any niche, ill-defined, problem in the areas of mathematical modeling, numerical simulation, and statistical analysis for our clients. And this, with no bureaucratic inertia.

For larger projects, or where specific advanced technical skills are needed, Spegegant relies on a network of senior experts, all of whom have academic research experience and a strong industry or consulting background.

With the right expertise in the right place, we bring peace of mind to our clients in complex projects.

We offer

Short-term reactivity

Long-term reliability

Advanced techniques without overkill

Targeted analyses

Work on niche or ill-defined problems

Peace of mind in complex projects

We value clarity above all

Complexity and uncertainty are no excuses for vagueness, mindless approximations, or spineless relativism.

We believe that where human health is at stake, sticking to explainable, traceable, modeling assumptions is an ethical imperative.

Modeling assumptions can have far-reaching implications. We can clearly convey them in both the area of infectious disease epidemiology and of health economics.

Our clients have scientific backgrounds or a keen interest in technical topics. By being transparent about our methods, we keep them involved and in control.

We encourage challenge and promote discussion, because this is how good science is done. We adapt models incrementally and run simulations on the fly to test hypotheses and scenarios as they come up from discussions.

We offer

High scientific standards

Transparency

Deep understanding of models

On the fly simulations to test ideas fast